1ujy Summary


Solution structure of SH3 domain in Rac/Cdc42 guanine nucleotide exchange factor(GEF) 6

A publication describing this structure is not available. The depositing authors are He, F.search; Muto, Y.search; Uda, H.search; Koshiba, S.search; Shirouzu, M.search; Terada, T.search; Kigawa, T.search; Inoue, M.search; Yabuki, T.search; Aoki, M.search; Seki, E.search; Matsuda, T.search; Hirota, H.search; Yoshida, M.search; Kobayashi, N.search; Tanaka, A.search; Osanai, T.search; Matsuo, Y.search; Ohara, O.search; Nagase, T.search; Kikuno, R.search; Nagayama, M.search; Yokoyama, S.search; RIKEN Structural Genomics/Proteomics Initiative (RSGI)search

The structure was determined using NMR spectroscopy and deposited in 2003.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Rho guanine nucleotide exchange factor 6. This molecule has the UniProt identifier Q15052 (ARHG6_HUMAN)search. The sample contained 76 residues which is < 90% of the natural sequence. Out of 76 residues 76 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Rho guanine nucleotide exchange factor 6 Q15052 (160-222) (ARHG6_HUMAN)search Homo sapienssearch < 90% 76 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q15052 (160 - 222) Rho guanine nucleotide exchange factor 6 Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A SH3-domainsearch SH3 Domainssearch Variant SH3 domainsearch
Chain InterPro annotation
A SH3 domainsearch