1uby Summary

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STRUCTURE OF FARNESYL PYROPHOSPHATE SYNTHETASE

The structure was published by Tarshis, L.C., Proteau, P.J., Kellogg, B.A., Sacchettini, J.C., and Poulter, C.D., in 1996 in a paper entitled "Regulation of product chain length by isoprenyl diphosphate synthases." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.4 Å and deposited in 1996.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of FARNESYL DIPHOSPHATE SYNTHASE. This molecule has the UniProt identifier P08836 (FPPS_CHICK)search. The sample contained 367 residues which is 100% of the natural sequence. Out of 367 residues 348 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A FARNESYL DIPHOSPHATE SYNTHASE P08836 (1-367) (FPPS_CHICK)search Gallus gallussearch 95% 367 94%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P08836 (1 - 367) FARNESYL DIPHOSPHATE SYNTHASE Gallus gallus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P08836) Isoprenyl diphosphate synthasessearch Farnesyl Diphosphate Synthasesearch PF00348: Polyprenyl synthetasesearch

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A (P08836) isoprenoid biosynthetic processsearch lipid metabolic processsearch sterol biosynthetic processsearch geranyl diphosphate biosynthetic processsearch steroid metabolic processsearch farnesyl diphosphate biosynthetic processsearch cholesterol biosynthetic processsearch steroid biosynthetic processsearch cholesterol metabolic processsearch cytoplasmsearch transferase activitysearch dimethylallyltranstransferase activitysearch metal ion bindingsearch geranyltranstransferase activitysearch

Chain InterPro annotation
A Polyprenyl synthetasesearch Terpenoid synthasesearch