› 1ua5

X-ray diffraction
2.5Å resolution

Non-fusion GST from S. japonicum in complex with glutathione

Released:
DOI: 10.2210/pdb1ua5/pdb
PDB entry 1ua5 coloured by chain, front view.
PDB entry 1ua5 coloured by chain, side view.
PDB entry 1ua5 coloured by chain, top view.
Source organism: Schistosoma japonicum
Primary publication:
Crystal structure of non-fused glutathione S-transferase from Schistosoma japonicum in complex with glutathione.
Kursula I, Heape AM, Kursula P
Protein Pept Lett 12 709-12 (2005)
PMID: 16522189

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140160 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase class-mu 26 kDa isozyme Chain: A
Molecule details ›
Chain: A
Length: 218 amino acids
Theoretical weight: 25.53 KDa
Source organism: Schistosoma japonicum
Expression system: Escherichia coli
UniProt:
  • Canonical: P08515 (Residues: 1-218; Coverage: 100%)
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand GSH 1 x GSH
1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P43212
Unit cell:
a: 92.527Å b: 92.527Å c: 57.657Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.172 0.169 0.221
Expression system: Escherichia coli

Quick links

Citations

8 citation in other articles

Autoinhibition of the formin Cappuccino in the absence of canonical autoinhibitory domains.
Bor et al. (2012)
7 more

11 mentions without citation

G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules.
Yang et al. (2020)
10 more