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EBI PDBe PDBeView

PDBe Entry: 1u9z view

Crystal Structure of Phosphoribosyl Diphosphate Synthase Complexed with AMP and Ribose 5-Phosphate
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.8 Å, R-factor: 24.0%, Free R-factor: 27.2%, Spacegroup: P 21 21 21
Released 23/08/2005, deposition: 11/08/2004, last revision: 24/02/2009
Authors Kadziola, A.search; Johansson, E.search; Jepsen, C.H.search; McGuire, J.search; Larsen, S.search; Hove-Jensen, B.search
Primary citation Novel class III phosphoribosyl diphosphate synthase: structure and properties of the tetrameric, phosphate-activated, non-allosterically inhibited enzyme from Methanocaldococcus jannaschii
J.MOL.BIOL.search vol:354, pag:815-828 (2005) [PubMed ID 16288921 ]search
Keywords PRPP synthase; ribose 5-phosphate; adenosine 5'-monophosphatesearch, TRANSFERASEsearch
EC 2.7.6.1 ExPASy BRENDA search (A B C D)
Organism Methanocaldococcus jannaschii 2190search(A B C D)
UniProt Ribose-phosphate pyrophosphokinase (EC 2.7.6.1) (RPPK) (Phosphoribosyl pyrophosphate synthetase) (P-Rib-PP synthetase) (PRPP synthetase) Q58761search (A B C D)
Solvent A, B, C, D
Related entries 1u9y
Polymers
Id Name Type UniProt Residues Observed
A, B, C, D Ribose-phosphate pyrophosphokinase Protein Q58761 (KPRS_METJA)search
 284 96%
Heterogens
Id Name Ligands
A, B, C, D OPEN FORM OF RIBOFURANOSE-5'-PHOSPHATE R5P search
B, D, C ADENOSINE MONOPHOSPHATE AMP search
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