1u3f Summary

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Structural and Functional Characterization of a 5,10-Methenyltetrahydrofolate Synthetase from Mycoplasma pneumoniae (GI: 13508087)

The structure was published by Chen, S., Shin, D.H., Pufan, R., Kim, R., and Kim, S.-H., in 2004 in a paper entitled "Crystal structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae (GI: 13508087) at 2.2 A resolution" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2004.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of 5,10-Methenyltetrahydrofolate Synthetase.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A 5,10-Methenyltetrahydrofolate Synthetase P75430 (1-164) (MTHFS_MYCPN)search Mycoplasma pneumoniae M129search 100% 189 86%
B 5,10-Methenyltetrahydrofolate Synthetase P75430 (1-164) (MTHFS_MYCPN)search Mycoplasma pneumoniae M129search 100% 189 86%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P75430 (1 - 164) 5,10-Methenyltetrahydrofolate Synthetase Mycoplasma pneumoniae

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P75430) Methenyltetrahydrofolate synthetasesearch NagB/RpiA/CoA transferase-likesearch PF01812: 5-formyltetrahydrofolate cyclo-ligase familysearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A, B (P75430) metabolic processsearch ATP bindingsearch nucleotide bindingsearch 5-formyltetrahydrofolate cyclo-ligase activitysearch metal ion bindingsearch ligase activitysearch cytoplasmsearch

Chain InterPro annotation
A, B 5-formyltetrahydrofolate cyclo-ligasesearch 5-formyltetrahydrofolate cyclo-ligase-like domainsearch