1twa Summary

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RNA polymerase II complexed with ATP

The structure was published by Westover, K.D., Bushnell, D.A., and Kornberg, R.D., in 2004 in a paper entitled "Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.2 Å and deposited in 2004.

The experimental data on which the structure is based was also deposited.

This entry contains 21 copies of 10 unique biopolymers (complete list).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterodecamers.


The are more than 5 unique protein polymers in this entry. More information is available on the Uniprot cross references page.

This entry contains 10 unique UniProt proteins:

UniProt accession Name Organism PDB
P04050 (1 - 1733) DNA-directed RNA polymerase II largest subunit Saccharomyces cerevisiae
P08518 (1 - 1224) DNA-directed RNA polymerase II 140 kDa polypeptide Saccharomyces cerevisiae
P16370 (1 - 318) DNA-directed RNA polymerase II 45 kDa polypeptide Saccharomyces cerevisiae
P20434 (1 - 215) DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide Saccharomyces cerevisiae
P20435 (1 - 155) DNA-directed RNA polymerases I, II, and III 23 kDa polypeptide Saccharomyces cerevisiae
P20436 (1 - 146) DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide Saccharomyces cerevisiae
P27999 (1 - 122) DNA-directed RNA polymerase II 14.2 kDa polypeptide Saccharomyces cerevisiae
P22139 (1 - 70) DNA-directed RNA polymerases I, II, and III 8.3 kDa polypeptide Saccharomyces cerevisiae
P38902 (1 - 120) DNA-directed RNA polymerase II 13.6 kDa polypeptide Saccharomyces cerevisiae
P40422 (1 - 70) DNA-directed RNA polymerases I, II, and III 7.7 kDa polypeptide Saccharomyces cerevisiae

For more information on cross references to other databases click Cross references in the menu on the left.