1tqp Summary


Crystal Structure of A. fulgidus Rio2 Serine Protein Kinase Bound to ATP

The structure was published by LaRonde-LeBlanc, N. and Wlodawer, A., in 2004 in a paper entitled "Crystal Structure of A. fulgidus Rio2 Defines a New Family of Serine Protein Kinases" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 2004.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of conserved hypothetical protein. This molecule has the UniProt identifier O30245 (RIO2_ARCFU)search. The sample contained 282 residues which is 100% of the natural sequence. Out of 282 residues 266 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A conserved hypothetical protein O30245 (1-282) (RIO2_ARCFU)search Archaeoglobus fulgidus DSM 4304search 100% 282 95%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
O30245 (1 - 282) conserved hypothetical protein Archaeoglobus fulgidus DSM 4304

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (O30245) Rio2 serine protein kinase N-terminal domainsearch, RIO1-like kinasessearch "winged helix" repressor DNA binding domainsearch, Phosphorylase Kinase; domain 1search, Transferase(Phosphotransferase) domain 1search PF01163: RIO1 familysearch, PF09202: Rio2, N-terminalsearch

Chain ID Molecular function (GO) Biological process (GO)
A (O30245) protein serine/threonine kinase activitysearch ATP bindingsearch catalytic activitysearch nucleotide bindingsearch metal ion bindingsearch protein kinase activitysearch transferase activity, transferring phosphorus-containing groupssearch transferase activitysearch kinase activitysearch protein phosphorylationsearch phosphorylationsearch

Chain InterPro annotation
A RIO kinasesearch Tyrosine-protein kinase, active sitesearch Protein kinase-like domainsearch Winged helix-turn-helix DNA-binding domainsearch RIO2 kinase, winged helix, N-terminalsearch RIO-like kinasesearch