› 1tp5

X-ray diffraction
1.54Å resolution

Crystal structure of PDZ3 domain of PSD-95 protein complexed with a peptide ligand KKETWV

Released:
DOI: 10.2210/pdb1tp5/pdb
PDB entry 1tp5 coloured by chain, front view.
PDB entry 1tp5 coloured by chain, side view.
PDB entry 1tp5 coloured by chain, top view.
Source organism: Rattus norvegicus
Entry authors: Saro D, Wawrzak Z, Martin P, Vickrey J, Paredes A, Kovari L, Spaller M

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-151881 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Disks large homolog 4 Chain: A
Molecule details ›
Chain: A
Length: 119 amino acids
Theoretical weight: 12.74 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P31016 (Residues: 302-402; Coverage: 14%)
Gene names: Dlg4, Dlgh4, Psd95
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
LYS-LYS-GLU-THR-TRP-VAL peptide ligand Chain: B
Molecule details ›
Chain: B
Length: 6 amino acids
Theoretical weight: 792 Da
Source organism: Rattus norvegicus
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.1
Spacegroup: P4132
Unit cell:
a: 89.978Å b: 89.978Å c: 89.978Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.191 0.229
Expression systems:
  • Escherichia coli
  • Not provided

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