 |
PDBe Entry: 1tmj 
Crystal structure of E.coli apo-HPPK(W89A) at 1.45 Angstrom resolution
 |
TRANSFERASE
|
|
X-RAY DIFFRACTION
|
|
Resolution: 1.45 Å, R-factor: 13.1%, Free R-factor: 17.4%, Spacegroup: P 1 21 1
|
|
21/06/2005, deposition: 10/06/2004, last revision: 24/02/2009
|
|
Blaszczyk, J.; Ji, X.
|
Is the Critical Role of Loop 3 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase in Catalysis Due to Loop-3 Residues Arginine-84 and Tryptophan-89? Site-Directed Mutagenesis, Biochemical, and Crystallographic Studies.
BIOCHEMISTRY vol:44, pag:8590-8599 (2005) [PubMed ID 15952765 ]
|
|
PYROPHOSPHOKINASE, PYROPHOSPHORYL TRANSFER, FOLATE, HPPK, 6-HYDROXYMETHYLPTERIN, 6-HYDROXYMETHYL-7, 8-DIHYDROPTERIN, ANTIMICROBIAL AGENT, DRUG DESIGN, X-RAY CRYSTALLOGRAPHY, POINT MUTANT, STRUCTURAL MUTAGENESIS, TRANSFERASE
|
|
2.7.6.3 ExPASy BRENDA (A)
|
|
Escherichia coli 562(A)
|
|
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK) P26281 (A)
|
|
A
|
|
1hka, 1eqm, 1eq0, 1q0n, 1ex8, 1cbk, 1dy3, 1f9y, 1f9h, 1g4c, 1hq2, 1im6, 1kbr, 1ru2, 1ru1, 1rtz, 1rb0, 1tmm
|
| A |
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase |
Protein |
P26281 (HPPK_ECOLI)
|
158 |
100% |
|
| A |
MAGNESIUM ION |
MG
|
| A |
CHLORIDE ION |
CL
|
|
|
