› 1tkq

Solution NMR

SOLUTION STRUCTURE OF A LINKED UNSYMMETRIC GRAMICIDIN IN A MEMBRANE-ISOELECTRICAL SOLVENTS MIXTURE IN THE PRESENCE OF CsCl

Released:
DOI: 10.2210/pdb1tkq/pdb
PDB entry 1tkq coloured by chain, front view.
PDB entry 1tkq coloured by chain, side view.
PDB entry 1tkq coloured by chain, top view.
Source organism: Brevibacillus brevis
Primary publication:
An asymmetric ion channel derived from gramicidin A. Synthesis, function and NMR structure.
Xie X, Al-Momani L, Reiss P, Griesinger C, Koert U
FEBS J 272 975-86 (2005)
PMID: 15691331

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162467 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
MINI-GRAMICIDIN A Chain: A
Molecule details ›
Chain: A
Length: 11 amino acids
Theoretical weight: 1.47 KDa
Source organism: Brevibacillus brevis
Expression system: Not provided
GRAMICIDIN A Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.81 KDa
Source organism: Brevibacillus brevis
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand SIN 1 x SIN
2 modified residues:
Ligand DVA 4 x DVA
Ligand DLE 7 x DLE

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

4 review citations

Ionic conductance of synthetic channels: analysis, lessons, and recommendations.
Chui et al. (2012)
3 more

2 mentions without citation

Paradoxical one-ion pore behavior of the long β-helical peptide of marine cytotoxic polytheonamide B.
Iwamoto et al. (2014)
1 more