1tf6 Summary

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CO-CRYSTAL STRUCTURE OF XENOPUS TFIIIA ZINC FINGER DOMAIN BOUND TO THE 5S RIBOSOMAL RNA GENE INTERNAL CONTROL REGION

The structure was published by Nolte, R.T., Conlin, R.M., Harrison, S.C., and Brown, R.S., in 1998 in a paper entitled "Differing roles for zinc fingers in DNA recognition: structure of a six-finger transcription factor IIIA complex." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.1 Å and deposited in 1998.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely DNA (5'-D(*AP*CP*GP*GP*GP*CP*CP*TP*GP*GP*TP*TP*AP*GP*TP*AP*C P*CP*TP*GP*GP*AP* TP*GP*GP*GP*AP*GP*AP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*TP*CP*TP*CP*CP*CP*AP*TP*CP*CP*AP*GP*GP*T P*AP*CP*TP*AP*AP* CP*CP*AP*GP*GP*CP*CP*CP*G)-3'), and PROTEIN (TRANSCRIPTION FACTOR IIIA).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A PROTEIN (TRANSCRIPTION FACTOR IIIA) P03001 (23-212) (TF3A_XENLA)search Xenopus laevissearch < 90% 190 95%
D PROTEIN (TRANSCRIPTION FACTOR IIIA) P03001 (23-212) (TF3A_XENLA)search Xenopus laevissearch < 90% 190 95%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P03001 (23 - 212) PROTEIN (TRANSCRIPTION FACTOR IIIA) Xenopus laevis

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, D Classic zinc finger, C2H2search Classic Zinc Fingersearch Zinc finger, C2H2 typesearch, Zinc-finger double domainsearch

Chain ID Molecular function (GO)
A, D (P03001) metal ion bindingsearch nucleic acid bindingsearch

Chain InterPro annotation
A, D Zinc finger, C2H2search Zinc finger C2H2-type/integrase DNA-binding domainsearch Zinc finger, C2H2-likesearch