› 1tf3

Solution NMR

TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES

Released:
DOI: 10.2210/pdb1tf3/pdb
PDB entry 1tf3 coloured by chain, ensemble of 22 models, front view.
PDB entry 1tf3 coloured by chain, ensemble of 22 models, side view.
PDB entry 1tf3 coloured by chain, ensemble of 22 models, top view.
Source organism: Xenopus laevis
Primary publication:
Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA.
Foster MP, Wuttke DS, Radhakrishnan I, Case DA, Gottesfeld JM, Wright PE
Nat Struct Biol 4 605-8 (1997)
PMID: 9253405

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114642 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct DNA molecules
Macromolecules (3 distinct):
Transcription factor IIIA Chain: A
Molecule details ›
Chain: A
Length: 92 amino acids
Theoretical weight: 10.69 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P03001 (Residues: 32-123; Coverage: 25%)
Gene name: gtf3a
Sequence domains: Zinc finger, C2H2 type
Structure domains: Classic Zinc Finger
5S RNA GENE Chain: E
Molecule details ›
Chain: E
Length: 15 nucleotides
Theoretical weight: 4.69 KDa
Source organism: Xenopus laevis
Expression system: Not provided
5S RNA GENE Chain: F
Molecule details ›
Chain: F
Length: 15 nucleotides
Theoretical weight: 4.49 KDa
Source organism: Xenopus laevis
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand ZN 3 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

Quick links

Citations

11 review citations

Zinc finger proteins: new insights into structural and functional diversity.
Laity et al. (2001)
10 more

10 mentions without citation

Host and Viral Zinc-Finger Proteins in COVID-19.
Esposito et al. (2022)
9 more