› 1t6w

Solution NMR

RATIONAL DESIGN OF A CALCIUM-BINDING ADHESION PROTEIN NMR, 20 STRUCTURES

Released:
DOI: 10.2210/pdb1t6w/pdb
PDB entry 1t6w coloured by chain, ensemble of 20 models, front view.
PDB entry 1t6w coloured by chain, ensemble of 20 models, side view.
PDB entry 1t6w coloured by chain, ensemble of 20 models, top view.
Source organism: Rattus norvegicus
Primary publication:
Design of a calcium-binding protein with desired structure in a cell adhesion molecule.
Yang W, Wilkins AL, Ye Y, Liu ZR, Li SY, Urbauer JL, Hellinga HW, Kearney A, van der Merwe PA, Yang JJ
J Am Chem Soc 127 2085-93 (2005)
PMID: 15713084

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140434 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
T-cell surface antigen CD2 Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 11.16 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P08921 (Residues: 23-121; Coverage: 31%)
Gene name: Cd2
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: ANNEAL
Expression system: Escherichia coli

Quick links

Citations

10 review citations

Theoretical and computational protein design.
Samish et al. (2011)
9 more

6 mentions without citation

Design of Calcium-Binding Proteins to Sense Calcium.
Tang et al. (2020)
5 more