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PDBe Entry: 1t6b view

Crystal structure of B. anthracis Protective Antigen complexed with human Anthrax toxin receptor
Summary
Header MEMBRANE PROTEIN/TOXINsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.5 Å, R-factor: 21.009%, Free R-factor: 26.572%, Spacegroup: P 21 21 21
Released 20/07/2004, deposition: 05/05/2004, last revision: 24/02/2009
Authors Santelli, E.search; Bankston, L.A.search; Leppla, S.H.search; Liddington, R.C.search
Primary citation Crystal structure of a complex between anthrax toxin and its host cell receptor
NATUREsearch vol:430, pag:905-908 (2004) [PubMed ID 15243628 ]search
Keywords Bacillus Anthracis; Anthrax toxin; X-ray crystallographysearch, MEMBRANE PROTEIN/TOXIN COMPLEXsearch
Organism Bacillus anthracis 1392search(X),Homo sapiens(human) 9606search(Y)
UniProt Protective antigen precursor (PA) (PA-83) (PA83) (Anthrax toxins translocating protein) [Contains: Protective antigen PA-20 (PA20); Protective antigen PA-63 (PA63)] P13423search (X)
Anthrax toxin receptor 2 precursor (Capillary morphogenesis gene 2 protein) (CMG-2) P58335search (Y)
Solvent X, Y
Polymers
Id Name Type UniProt Residues Observed
X Protective Antigen Protein P13423 (PAG_BACAN)search
735 91%
Y Anthrax toxin receptor 2 Protein P58335 (ANTR2_HUMAN)search
189 89%
Heterogens
Id Name Ligands
X CALCIUM ION CA search
Y MANGANESE (II) ION MN search
X SODIUM ION NA search
X TETRAETHYLENE GLYCOL PG4 search
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