1t5x Summary details

spacer HLA-DR1 in complex with a synthetic peptide (AAYSDQATPLLLSPR) and the superantigen SEC3-3B2
Header IMMUNE SYSTEMsearch
Experiment Resolution: 2.5 Å, R-factor: 21.1%, Free R-factor: 24.1%, Spacegroup: H 3
Released 17/08/2004, deposition: 05/05/2004, last revision: 24/02/2009
Authors Zavala-Ruiz, Z.search; Strug, I.search; Anderson, M.W.search; Gorski, J.search; Stern, L.J.search
Primary citation A Polymorphic Pocket at the P10 Position Contributes to Peptide Binding Specificity in Class II MHC Proteins
CHEM.BIOL.search vol:11, pag:1395-1402 (2004) [PubMed 15489166 ]search
Keywords MHC class II; major histocompatibiloty complex protein; HLA-DR1; superantigen; antigen; peptidesearch, IMMUNE SYSTEMsearch
Organism Homo sapiens(human) 9606search(A B),Staphylococcus aureus 1280search(D)
UniProt P01903search (A)
P04229search (B)
P27705search (C)
P0A0L5search (D)
Solvent A, B, C, D
Related entries 1aqd, 1dlh, 1klu, 1pyw, 1t5w
Chain Id Name Type UniProt Residues in sample sequence % of sample sequence observed
A HLA class II histocompatibility antigen, DR alpha chain Protein P01903 (DRA_HUMAN)search
181 98%
B HLA class II histocompatibility antigen, DRB1-1 beta chain Protein P04229 (2B11_HUMAN)search
190 100%
C 15-mer peptide fragment of Regulatory protein MIG1 Protein P27705 (MIG1_YEAST)search
15 86%
D Enterotoxin type C-3 Protein P0A0L5 (ENTC3_STAAU)search
239 96%