1t5r Summary

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STRUCTURE OF THE PANTON-VALENTINE LEUCOCIDIN S COMPONENT FROM STAPHYLOCOCCUS AUREUS

There is a Quite Interesting Protein Structure article for this entry.

The structure was published by Guillet, V., Roblin, P., Werner, S., et al., Menestrina, G., Monteil, H., and Mourey, L., in 2004 in a paper entitled "Crystal structure of leucotoxin S component: new insight into the Staphylococcal beta-barrel pore-forming toxins." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2004.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of LukS-PV.

The molecule most likely forms homooctamers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A LukS-PV Q783R1 (29-312) (Q783R1_9CAUD)search Staphylococcus phage phiSLTsearch 91% 284 95%
B LukS-PV Q783R1 (29-312) (Q783R1_9CAUD)search Staphylococcus phage phiSLTsearch 91% 284 95%
C LukS-PV Q783R1 (29-312) (Q783R1_9CAUD)search Staphylococcus phage phiSLTsearch 91% 284 95%
D LukS-PV Q783R1 (29-312) (Q783R1_9CAUD)search Staphylococcus phage phiSLTsearch 91% 284 95%
E LukS-PV Q783R1 (29-312) (Q783R1_9CAUD)search Staphylococcus phage phiSLTsearch 91% 284 95%
F LukS-PV Q783R1 (29-312) (Q783R1_9CAUD)search Staphylococcus phage phiSLTsearch 91% 284 95%
G LukS-PV Q783R1 (29-312) (Q783R1_9CAUD)search Staphylococcus phage phiSLTsearch 91% 284 95%
H LukS-PV Q783R1 (29-312) (Q783R1_9CAUD)search Staphylococcus phage phiSLTsearch 91% 284 95%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q783R1 (29 - 312) LukS-PV Staphylococcus phage PVL

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C, D, E, F, G, H Leukocidin (pore-forming toxin)search Leukocidin-likesearch Leukocidin/Hemolysin toxin familysearch

Chain ID Cellular component (GO) Biological process (GO)
A, B, C, D, E, F, G, H (Q783R1) extracellular regionsearch cytolysis in other organismsearch pathogenesissearch

Chain InterPro annotation
A, B, C, D, E, F, G, H Bi-component toxin, staphylococcisearch Leukocidin/porinsearch