1t2r Summary


Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain

The structure was published by Lingel, A., Simon, B., Izaurralde, E., and Sattler, M., in 2004 in a paper entitled "Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2004.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely 5'-R(*CP*UP*CP*AP*C)-3' and Argonaute 2.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Argonaute 2 Q9VUQ5 (602-720) (AGO2_DROME)search Drosophila melanogastersearch < 90% 123 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9VUQ5 (602 - 720) Argonaute 2 Drosophila melanogaster

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A PAZ domainsearch paz domainsearch PAZ domainsearch
Chain InterPro annotation
A PAZ domainsearch