spacer Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases
SCOP: Structural Classification of Proteins
Domain 106150search
SCCS c.31.1.5search
Description 1szd A:
Comments complexed with apr, cl, gol, zn
Polymers A
UniProt P53686
Class Alpha and beta proteins (a/b) search
Fold DHS-like NAD/FAD-binding domain search
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
Superfamily DHS-like NAD/FAD-binding domain search
binds cofactor molecules in the opposite direction than classical Rossmann fold
Family Sir2 family of transcriptional regulators search
silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
Protein Hst2 search