spacer Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD+-dependent Sir2 histone/protein deacetylases
UniProt sequence   UniProt   CATH   Pfam   SCOP   Secondary structure   UniProt features   FASTA string  

Chain A: NAD-dependent deacetylase HST2

1 M A S M S V S T A S T E M S V R K I A A H M K S N P N A K V I F M V G A G I S T S C G I P D F R S P G T G L Y H N L A R
M S V S T A S T E M S V R K I A A H M K S N P N A K V I F M V G A G I S T S C G I P D F R S P G T G L Y H N L A R
1
61 L K L P Y P E A V F D V D F F Q S D P L P F Y T L A K E L Y P G N F R P S K F H Y L L K L F Q D K D V L K R V Y T Q N I
L K L P Y P E A V F D V D F F Q S D P L P F Y T L A K E L Y P G N F R P S K F H Y L L K L F Q D K D V L K R V Y T Q N I
121 D T L E R Q A G V K D D L I I E A H G S F A H C H C I G C G K V Y P P Q V F K S K L A E H P I K D F V K C D V C G E L V
D T L E R Q A G V K D D L I I E A H G S F A H C H C I G C G K V Y P P Q V F K S K L A E H P I K D F V K C D V C G E L V
181 K P A I V F F G E D L P D S F S E T W L N D S E W L R E K I T T S G K H P Q Q P L V I V V G T S L A V Y P F A S L P E E
K P A I V F F G E D L P D S F S E T W L N D S E W L R E K I T T S G K H P Q Q P L V I V V G T S L A V Y P F A S L P E E
241 I P R K V K R V L C N L E T V G D F K A N K R P T D L I V H Q Y S D E F A E Q L V E E L G W Q E D F E K I L T A Q
I P R K V K R V L C N L E T V G D F K A N K R P T D L I V H Q Y S D E F A E Q L V E E L G W Q E D F E K I L T A Q
294

Regions

UniProt

P53686
1 .. 294 > 1 .. 294 (PDB)

Pfam

PF02146
32 .. 230 (PDB)

Chain B: Histone H4 peptide

1 K G G A X R H R K I
K G G A K R H R K I
13 22

Regions

UniProt

P02309
13 .. 22 > 12 .. 21 (PDB)
spacer