Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 1
The structure was published by Breitenlechner, C.B., Wegge, T., Berillon, L., et al., Huber, R., Engh, R.A., and Masjost, B., in 2004 in a paper entitled "Structure-based optimization of novel azepane derivatives as PKB inhibitors" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.49 Å and deposited in 2004.
The experimental data on which the structure is based was not deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely cAMP-dependent protein kinase, alpha-catalytic subunit and cAMP-dependent protein kinase inhibitor, alpha form.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: