1srp Summary



The structure was published by Hamada, K., Hata, Y., Katsuya, Y., Hiramatsu, H., Fujiwara, T., and Katsube, Y., in 1996 in a paper entitled "Crystal structure of Serratia protease, a zinc-dependent proteinase from Serratia sp. E-15, containing a beta-sheet coil motif at 2.0 A resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1994.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of SERRALYSIN. This molecule has the UniProt identifier P07268 (PRZN_SERME)search. The sample contained 471 residues which is 97% of the natural sequence. Out of 471 residues 468 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A SERRALYSIN P07268 (17-487) (PRZN_SERME)search Serratia sp. E-15search 97% 471 99%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P07268 (17 - 487) SERRALYSIN Serratia sp. E-15

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P07268) Serralysin-like metalloprotease, C-terminal domainsearch, Serralysin-like metalloprotease, catalytic (N-terminal) domainsearch Alkaline Protease, subunit P, domain 1search, Collagenase (Catalytic Domain)search PF00413: Matrixinsearch, PF08548: Peptidase M10 serralysin C terminalsearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P07268) metallopeptidase activitysearch zinc ion bindingsearch metalloendopeptidase activitysearch calcium ion bindingsearch peptidase activitysearch metal ion bindingsearch hydrolase activitysearch proteolysissearch extracellular spacesearch extracellular matrixsearch extracellular regionsearch

Chain InterPro annotation
A Haemolysin-type calcium-binding repeatsearch Peptidase M10, metallopeptidasesearch Peptidase, metallopeptidasesearch Serralysin-like metalloprotease, C-terminalsearch Peptidase M10 serralysin C-terminal domainsearch Peptidase M10Bsearch Hemolysin-type calcium-binding conserved sitesearch Metallopeptidase, catalytic domainsearch