1srb Summary

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CONFORMATIONAL STUDIES ON SRTB, A NON-SELECTIVE ENDOTHELIN RECEPTOR AGONIST, AND ON IRL 1620, AN ETB RECEPTOR SPECIFIC AGONIST

The structure was published by Atkins, A.R., Martin, R.C., and Smith, R., in 1995 in a paper entitled "1H NMR studies of sarafotoxin SRTb, a nonselective endothelin receptor agonist, and IRL 1620, an ETB receptor-specific agonist." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1994.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Sarafotoxins precursor. This molecule has the UniProt identifier P13208 (SRTX_ATREN)search. The sample contained 21 residues which is < 90% of the natural sequence. Out of 21 residues 21 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Sarafotoxins precursor P13208 (430-450) (SRTX_ATREN)search Atractaspis andersoniisearch < 90% 21 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P13208 (430 - 450) Sarafotoxins precursor Atractaspis andersonii

Chain Structural classification (SCOP) Sequence family (Pfam)
A Endothelin-likesearch Endothelin familysearch

Chain ID Biological process (GO) Cellular component (GO)
A (P13208) regulation of vasoconstrictionsearch extracellular regionsearch

Chain InterPro annotation
A Endothelin-like toxinsearch Endothelin-like toxin, conserved sitesearch