1sph Summary

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REFINED STRUCTURES OF THE ACTIVE S83C AND IMPAIRED S46D HPRS: EVIDENCE THAT PHOSPHORYLATION DOES NOT REQUIRE A BACKBONE CONFORMATIONAL TRANSITION

The structure was published by Liao, D.I. and Herzberg, O., in 1994 in a paper entitled "Refined structures of the active Ser83-->Cys and impaired Ser46-->Asp histidine-containing phosphocarrier proteins." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1994.

The experimental data on which the structure is based was not deposited.

This PDB entry contains multiple copies of the structure of HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR.

The molecule most likely forms homodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR P08877 (1-88) (PTHP_BACSU)search Bacillus subtilis subsp. subtilis str. 168search 99% 88 98%
B HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR P08877 (1-88) (PTHP_BACSU)search Bacillus subtilis subsp. subtilis str. 168search 99% 88 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P08877 (1 - 88) HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR Bacillus subtilis

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P08877) HPr-likesearch Histidine-containing Protein; Chain: A;search PF00381: PTS HPr component phosphorylation sitesearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A, B (P08877) regulation of carbohydrate utilizationsearch regulation of transcription, DNA-templatedsearch phosphoenolpyruvate-dependent sugar phosphotransferase systemsearch transportsearch phosphorylationsearch carbohydrate transportsearch transcription, DNA-templatedsearch protein phosphorylationsearch transferase activitysearch protein bindingsearch kinase activitysearch protein serine/threonine kinase activitysearch cytoplasmsearch

Chain InterPro annotation
A, B Phosphocarrier HPr protein-likesearch Phosphotransferase system, HPr histidine phosphorylation sitesearch