1snz Summary


Crystal structure of apo human galactose mutarotase

The structure was published by Thoden, J.B., Timson, D.J., Reece, R.J., and Holden, H.M., in 2004 in a paper entitled "Molecular structure of human galactose mutarotase" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.2 Å and deposited in 2004.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of aldose 1-epimerase.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A aldose 1-epimerase Q96C23 (1-342) (GALM_HUMAN)search Homo sapienssearch 100% 344 100%
B aldose 1-epimerase Q96C23 (1-342) (GALM_HUMAN)search Homo sapienssearch 100% 344 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q96C23 (1 - 342) aldose 1-epimerase Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (Q96C23) Aldose 1-epimerase (mutarotase)search Beta-galactosidase; Chain A, domain 5search PF01263: Aldose 1-epimerasesearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B (Q96C23) isomerase activitysearch carbohydrate bindingsearch catalytic activitysearch aldose 1-epimerase activitysearch hexose metabolic processsearch carbohydrate metabolic processsearch galactose metabolic processsearch glucose metabolic processsearch extracellular vesicular exosomesearch cytoplasmsearch

Chain InterPro annotation
A, B Aldose 1-/Glucose-6-phosphate 1-epimerasesearch Galactose mutarotase-like domainsearch Glycoside hydrolase-type carbohydrate-binding, subgroupsearch Aldose 1-epimerasesearch Aldose 1-epimerase, conserved sitesearch