spacer HLA-DR1 complexed with a 13 residue HIV capsid peptide
CATH: Protein Structure Classification
CATH code 3.10.320.10 search
Domains
1sjhA01
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a. Fragment: extracellular domain of hla-dra*0101. Synonym: mhc class ii antigen dra. Engineered: yes. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b. Fragment: extracellular domain of hla-drb*0101. Synonym: mhc class i antigen drb1*1, dr-1, dr1. Engineered: yes.Gag polyprotein. Chain: c. Fragment: 13 residue peptide from hiv-1 gagcapsid protein. Engineered: yes. Enterotoxin type c-3. Chain: d. Fragment: sec3 variant 3b2. Synonym: sec3. Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Polymers A
Hierarchy
Class Alpha Betasearch
Architecture Roll search
Topology Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
Homologous superfamily Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
 
CATH code 2.60.40.10 search
Domains
1sjhA02
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a. Fragment: extracellular domain of hla-dra*0101. Synonym: mhc class ii antigen dra. Engineered: yes. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b. Fragment: extracellular domain of hla-drb*0101. Synonym: mhc class i antigen drb1*1, dr-1, dr1. Engineered: yes.Gag polyprotein. Chain: c. Fragment: 13 residue peptide from hiv-1 gagcapsid protein. Engineered: yes. Enterotoxin type c-3. Chain: d. Fragment: sec3 variant 3b2. Synonym: sec3. Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Polymers A
Hierarchy
Class Mainly Betasearch
Architecture Sandwich search
Topology Immunoglobulin-like search
Homologous superfamily Immunoglobulins search
 
CATH code 3.10.320.10 search
Domains
1sjhB01
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a. Fragment: extracellular domain of hla-dra*0101. Synonym: mhc class ii antigen dra. Engineered: yes. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b. Fragment: extracellular domain of hla-drb*0101. Synonym: mhc class i antigen drb1*1, dr-1, dr1. Engineered: yes.Gag polyprotein. Chain: c. Fragment: 13 residue peptide from hiv-1 gagcapsid protein. Engineered: yes. Enterotoxin type c-3. Chain: d. Fragment: sec3 variant 3b2. Synonym: sec3. Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Polymers B
Hierarchy
Class Alpha Betasearch
Architecture Roll search
Topology Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
Homologous superfamily Class II Histocompatibility Antigen, M Beta Chain; Chain B, domain 1 search
 
CATH code 2.60.40.10 search
Domains
1sjhB02
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a. Fragment: extracellular domain of hla-dra*0101. Synonym: mhc class ii antigen dra. Engineered: yes. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b. Fragment: extracellular domain of hla-drb*0101. Synonym: mhc class i antigen drb1*1, dr-1, dr1. Engineered: yes.Gag polyprotein. Chain: c. Fragment: 13 residue peptide from hiv-1 gagcapsid protein. Engineered: yes. Enterotoxin type c-3. Chain: d. Fragment: sec3 variant 3b2. Synonym: sec3. Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Polymers B
Hierarchy
Class Mainly Betasearch
Architecture Sandwich search
Topology Immunoglobulin-like search
Homologous superfamily Immunoglobulins search
 
CATH code 2.40.50.110 search
Domains
1sjhD01
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a. Fragment: extracellular domain of hla-dra*0101. Synonym: mhc class ii antigen dra. Engineered: yes. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b. Fragment: extracellular domain of hla-drb*0101. Synonym: mhc class i antigen drb1*1, dr-1, dr1. Engineered: yes.Gag polyprotein. Chain: c. Fragment: 13 residue peptide from hiv-1 gagcapsid protein. Engineered: yes. Enterotoxin type c-3. Chain: d. Fragment: sec3 variant 3b2. Synonym: sec3. Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Polymers D
Uniprot P0A0L5
Hierarchy
Class Mainly Betasearch
Architecture Beta Barrel search
Topology OB fold (Dihydrolipoamide Acetyltransferase, E2P) search
Homologous superfamily OB fold (Dihydrolipoamide Acetyltransferase, E2P) search
 
CATH code 3.10.20.120 search
Domains
1sjhD02
Name Hla class ii histocompatibility antigen, dr alpha chain. Chain: a. Fragment: extracellular domain of hla-dra*0101. Synonym: mhc class ii antigen dra. Engineered: yes. Hla class ii histocompatibility antigen, drb1-1 beta chain. Chain: b. Fragment: extracellular domain of hla-drb*0101. Synonym: mhc class i antigen drb1*1, dr-1, dr1. Engineered: yes.Gag polyprotein. Chain: c. Fragment: 13 residue peptide from hiv-1 gagcapsid protein. Engineered: yes. Enterotoxin type c-3. Chain: d. Fragment: sec3 variant 3b2. Synonym: sec3. Engineered: yes. Mutation: yes
Source Homo sapiens. Human. Organism_taxid: 9606. Gene: hla-dra. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Polymers D
Uniprot P0A0L5
Hierarchy
Class Alpha Betasearch
Architecture Roll search
Topology Ubiquitin-like (UB roll) search
Homologous superfamily Ubiquitin-like (UB roll) search
 
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