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EBI PDBe PDBeView

PDBe Entry: 1sgd view

ASP 18 VARIANT OF TURKEY OVOMUCOID INHIBITOR THIRD DOMAIN COMPLEXED WITH STREPTOMYCES GRISEUS PROTEINASE B AT PH 6.5
Summary
Header HYDROLASE/HYDROLASE INHIBITORsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.8 Å, R-factor: 15.7%, Spacegroup: P 1 21 1
Released 26/08/2003, deposition: 25/03/1999, last revision: 24/02/2009
Authors Huang, K.search; Lu, W.search; Anderson, S.search; Laskowski Jr., M.search; James, M.N.G.search
Primary citation Recruitment of a Buried K+ Ion to Stabilize the Negative Charge of Ionized P1 in the Hydrophobic Pocket: Crystal Structures of Glu18, Gln18, Asp18 and Asn18 Variants of Turkey Ovomucoid Inhibitor Third Domain Complexed with Streptomyces griseus Protease B at Various pH's
To be Published
Keywords COMPLEX (SERINE PROTEASE/INHIBITOR)search, SERINE PROTEINASEsearch, PROTEIN INHIBITORsearch, HYDROLASE/HYDROLASE INHIBITOR COMPLEXsearch
EC 3.4.21.81 ExPASy BRENDA search (E)
Organism Streptomyces griseus 1911search(E),Meleagris gallopavo(turkey) 9103search(I)
UniProt Streptogrisin-B precursor (EC 3.4.21.81) (Serine protease B) (SGPB) (Pronase enzyme B) P00777search (E)
Ovomucoid P68390search (I)
Solvent E, I
Polymers
Id Name Type UniProt Residues Observed
E Streptogrisin B Protein P00777 (PRTB_STRGR)search
 185 100%
I Ovomucoid Protein P68390 (IOVO_MELGA)search
 51 100%
Heterogens
Id Name Ligands
E PHOSPHATE ION PO4 search
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