1scm Summary



The structure was published by Xie, X., Harrison, D.H., Schlichting, I., et al., Kalabokis, V.N., Szent-Gyorgyi, A.G., and Cohen, C., in 1994 in a paper entitled "Structure of the regulatory domain of scallop myosin at 2.8 A resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.8 Å and deposited in 1994.

The experimental data on which the structure is based was not deposited.

This PDB entry contains a complex of 3 biomacromolecules, namely MYOSIN HEAVY CHAIN, MYOSIN REGULATORY LIGHT CHAIN, and MYOSIN ESSENTIAL LIGHT CHAIN.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms heterotrimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A MYOSIN HEAVY CHAIN P24733 (777-836) (MYS_ARGIR)search Argopecten irradianssearch < 90% 60 100%
B MYOSIN REGULATORY LIGHT CHAIN P13543 (13-157) (MLR_ARGIR)search Argopecten irradianssearch 92% 145 95%
C MYOSIN ESSENTIAL LIGHT CHAIN P07291 (5-153) (MLE_ARGIR)search Argopecten irradianssearch 95% 149 100%

This entry contains 3 unique UniProt proteins:

UniProt accession Name Organism PDB
P24733 (777 - 836) MYOSIN HEAVY CHAIN Argopecten irradians
P13543 (13 - 157) MYOSIN REGULATORY LIGHT CHAIN Argopecten irradians
P07291 (5 - 153) MYOSIN ESSENTIAL LIGHT CHAIN Argopecten irradians

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Myosin, subunit Asearch IQ calmodulin-binding motifsearch
B (P13543) Calmodulin-likesearch EF-handsearch PF00036: EF handsearch
C (P07291) Calmodulin-likesearch EF-handsearch

Chain ID Molecular function (GO) Cellular component (GO)
B (P13543) metal ion bindingsearch calcium ion bindingsearch myosin complexsearch
C (P07291) calcium ion bindingsearch myosin complexsearch

Chain InterPro annotation
A IQ motif, EF-hand binding sitesearch Myosin-like IQ motif-containing domainsearch P-loop containing nucleoside triphosphate hydrolasesearch
B EF-hand domainsearch EF-hand domain pairsearch EF-Hand 1, calcium-binding sitesearch
C EF-hand domainsearch EF-hand domain pairsearch