1sca Summary



The structure was published by Fitzpatrick, P.A., Steinmetz, A.C., Ringe, D., and Klibanov, A.M., in 1993 in a paper entitled "Enzyme crystal structure in a neat organic solvent." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1993.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of SUBTILISIN CARLSBERG. This molecule has the UniProt identifier P00780 (SUBT_BACLI)search. The sample contained 274 residues which is < 90% of the natural sequence. Out of 274 residues 274 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A SUBTILISIN CARLSBERG P00780 (106-379) (SUBT_BACLI)search Bacillus licheniformissearch < 90% 274 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P00780 (106 - 379) SUBTILISIN CARLSBERG Bacillus licheniformis

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Subtilasessearch Rossmann foldsearch Subtilase familysearch

Chain ID Molecular function (GO) Biological process (GO)
A (P00780) serine-type endopeptidase activitysearch proteolysissearch

Chain InterPro annotation
A Peptidase S8/S53 domainsearch Peptidase S8, subtilisin-relatedsearch Peptidase S8, subtilisin, His-active sitesearch Peptidase S8, subtilisin, Asp-active sitesearch Peptidase S8, subtilisin, Ser-active sitesearch