1sbx Summary


Crystal structure of the Dachshund-homology domain of human SKI

The structure was published by Wilson, J.J., Malakhova, M., Zhang, R., Joachimiak, A., and Hegde, R.S., in 2004 in a paper entitled "Crystal Structure of the Dachshund Homology Domain of human SKI" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.65 Å and deposited in 2004.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Ski oncogene. This molecule has the UniProt identifier P12755 (SKI_HUMAN)search. The sample contained 106 residues which is < 90% of the natural sequence. Out of 106 residues 106 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Ski oncogene P12755 (91-192) (SKI_HUMAN)search Homo sapienssearch < 90% 106 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P12755 (91 - 192) Ski oncogene Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Dachshund-homology domainsearch Putative DNA-binding domainsearch SKI/SNO/DAC familysearch

Chain ID Biological process (GO) Cellular component (GO)
A (P12755) transcription, DNA-templatedsearch nucleussearch

Chain InterPro annotation
A Transforming protein Skisearch DNA binding domain, putativesearch Transcription regulator SKI/SnoNsearch Ski oncogenesearch