1sbj Summary


NMR Structure of the Mg2+-loaded C Terminal Domain of Cardiac Troponin C Bound to the N Terminal Domain of Cardiac Troponin I

The structure was published by Finley, N.L., Howarth, J.W., and Rosevear, P.R., in 2004 in a paper entitled "Structure of the Mg2+-loaded C-lobe of cardiac troponin C bound to the N-domain of cardiac troponin I: comparison with the Ca2+-loaded structure." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2004.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Troponin C, slow skeletal and cardiac muscles. This molecule has the UniProt identifier P09860 (TNNC1_CHICK)search. The sample contained 81 residues which is < 90% of the natural sequence. Out of 81 residues 81 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Troponin C, slow skeletal and cardiac muscles P09860 (81-161) (TNNC1_CHICK)search Gallus gallussearch 99% 81 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P09860 (81 - 161) Troponin C, slow skeletal and cardiac muscles Gallus gallus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P09860) Calmodulin-likesearch EF-handsearch PF13499: EF-hand domain pairsearch, PF13833: EF-hand domain pairsearch

Chain ID Molecular function (GO)
A (P09860) calcium ion bindingsearch

Chain InterPro annotation
A EF-hand domainsearch EF-hand domain pairsearch EF-Hand 1, calcium-binding sitesearch