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PDBe Entry: 1sa0 
TUBULIN-COLCHICINE: STATHMIN-LIKE DOMAIN COMPLEX
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CELL CYCLE
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X-RAY DIFFRACTION
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Resolution: 3.58 Å, R-factor: 23.252%, Free R-factor: 24.852%, Spacegroup: P 65
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23/03/2004, deposition: 06/02/2004, last revision: 24/02/2009
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Ravelli, R.B.; Gigant, B.; Curmi, P.A.; Jourdain, I.; Lachkar, S.; Sobel, A.; Knossow, M.
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Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain.
NATURE vol:428, pag:198-202 (2004) [PubMed ID 15014504 ]
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ALPHA-TUBULIN, BETA-TUBULIN, COLCHICINE, GTPASE, MICROTUBULE PODOPHYLLOTOXIN, STATHMIN, TUBULIN, CELL CYCLE
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Bos taurus(cattle) 9913(A C B D),Rattus norvegicus(Norway rat) 10116(E)
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Tubulin alpha-1D chain Q2HJ86 (A C)
Tubulin beta-2B chain Q6B856 (B D)
Stathmin-4 (Stathmin-like protein B3) (RB3) P63043 (E)
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1sa1
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| A, C |
Tubulin alpha chain |
Protein |
Q2HJ86 (TBA1D_BOVIN)
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451 |
94% |
| B, D |
Tubulin beta chain |
Protein |
Q6B856 (TBB2B_BOVIN)
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445 |
94% |
| E |
Stathmin 4 |
Protein |
P63043 (STMN4_RAT)
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142 |
87% |
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| A, B, C |
MAGNESIUM ION |
MG
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| A, C |
GUANOSINE-5'-TRIPHOSPHATE |
GTP
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| B, D |
GUANOSINE-5'-DIPHOSPHATE |
GDP
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| B, D |
2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE |
CN2
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