X-ray structure of the human mitogen-activated protein kinase kinase 2 (MEK2)in a complex with ligand and MgATP
The structure was published by Ohren, J.F., Chen, H., Pavlovsky, A., et al., Barrett, S., Tecle, H., and Hasemann, C.A., in 2004 in a paper entitled "Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.2 Å and deposited in 2004.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of Dual specificity mitogen-activated protein kinase kinase 2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: