1s3p Summary


Crystal structure of rat alpha-parvalbumin S55D/E59D mutant

The structure was published by Lee, Y.H., Tanner, J.J., Larson, J.D., and Henzl, M.T., in 2004 in a paper entitled "Crystal Structure of a High-Affinity Variant of Rat alpha-Parvalbumin." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2004.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Parvalbumin alpha. This molecule has the UniProt identifier P02625 (PRVA_RAT)search. The sample contained 109 residues which is 99% of the natural sequence. Out of 109 residues 109 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Parvalbumin alpha P02625 (2-110) (PRVA_RAT)search Rattus norvegicussearch 99% 109 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P02625 (2 - 110) Parvalbumin alpha Rattus norvegicus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P02625) Parvalbuminsearch EF-handsearch PF13499: EF-hand domain pairsearch, PF13833: EF-hand domain pairsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P02625) calcium ion bindingsearch protein homodimerization activitysearch protein heterodimerization activitysearch metal ion bindingsearch cytoplasmsearch axonsearch nucleussearch protein complexsearch neuronal cell bodysearch cytosolic calcium ion homeostasissearch

Chain InterPro annotation
A EF-hand domainsearch Parvalbuminsearch EF-hand domain pairsearch EF-Hand 1, calcium-binding sitesearch