› 1s3p

X-ray diffraction
2Å resolution

Crystal structure of rat alpha-parvalbumin S55D/E59D mutant

Released:
DOI: 10.2210/pdb1s3p/pdb
PDB entry 1s3p coloured by chain, front view.
PDB entry 1s3p coloured by chain, side view.
PDB entry 1s3p coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Crystal structure of a high-affinity variant of rat alpha-parvalbumin.
Lee YH, Tanner JJ, Larson JD, Henzl MT
Biochemistry 43 10008-17 (2004)
PMID: 15287728

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135966 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Parvalbumin alpha Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 11.83 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P02625 (Residues: 2-110; Coverage: 99%)
Gene names: Pva, Pvalb
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P21212
Unit cell:
a: 61.47Å b: 51.57Å c: 30.75Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.181 0.221
Expression system: Escherichia coli

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Citations

1 review citation

Calcium mishandling in diastolic dysfunction: mechanisms and potential therapies.
Asp et al. (2013)
5 other articles

9 mentions without citation

Structure-based protein function prediction using graph convolutional networks.
Gligorijević et al. (2021)
8 more