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EBI PDBe PDBeView

PDBe Entry: 1s38 view

CRYSTAL STRUCTURE OF TGT IN COMPLEX WITH 2-AMINO-8-METHYLQUINAZOLIN-4(3H)-ONE
Summary
Header TRANSFERASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.81 Å, R-factor: 19.7%, Free R-factor: 22.2%, Spacegroup: C 1 2 1
Released 27/07/2004, deposition: 12/01/2004, last revision: 24/02/2009
Authors Meyer, E.A.search; Furler, M.search; Diederich, F.search; Brenk, R.search; Klebe, G.search
Primary citation Synthesis and In vitro Evaluation of 2-Aminoquinazolin-4(3H)-one-based Inhibitors for tRNA-Guanine Transglycosylase (TGT)
HELV.CHIM.ACTAsearch vol:87, pag:1333-1356 (2004)
Keywords TRANSFERASEsearch
EC 2.4.2.29 ExPASy BRENDA search (A)
Organism Zymomonas mobilis 542search(A)
UniProt Queuine tRNA-ribosyltransferase (EC 2.4.2.29) (tRNA-guanine transglycosylase) (Guanine insertion enzyme) P28720search (A)
Solvent A
Related entries 1pud, 1s39
Polymers
Id Name Type UniProt Residues Observed
A tRNA guanine transglycosylase Protein P28720 (TGT_ZYMMO)search
 386 94%
Heterogens
Id Name Ligands
A ZINC ION ZN search
A 2-AMINO-8-METHYLQUINAZOLIN-4(3H)-ONE MAQ search
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