1s1n Summary

pdbe.org/1s1n
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SH3 domain of human nephrocystin

The structure was published by le Maire, A., Weber, T., Saunier, S., et al., Antignac, C., Ducruix, A., and Dardel, F., in 2005 in a paper entitled "Solution NMR structure of the SH3 domain of human nephrocystin and analysis of a mutation-causing juvenile nephronophthisis." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2004.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Nephrocystin 1. This molecule has the UniProt identifier O15259 (NPHP1_HUMAN)search. The sample contained 68 residues which is < 90% of the natural sequence. Out of 68 residues 60 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Nephrocystin 1 O15259 (147-212) (NPHP1_HUMAN)search Homo sapienssearch < 90% 68 88%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
O15259 (147 - 212) Nephrocystin 1 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A SH3 Domainssearch SH3 domainsearch
Chain InterPro annotation
A SH3 domainsearch