Crystal structure of the VDR LBD complexed to seocalcitol.
The structure was published by Tocchini-Valentini, G., Rochel, N., Wurtz, J.M., and Moras, D., in 2004 in a paper entitled "Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2004.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Vitamin D3 receptor. This molecule has the UniProt identifier P11473 (VDR_HUMAN). The sample contained 263 residues which is < 90% of the natural sequence. Out of 263 residues 253 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: