1rz8 Summary

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CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 17B

The structure was published by Huang, C.C., Venturi, M., Majeed, S., et al., Choe, H., Farzan, M., and Kwong, P.D., in 2004 in a paper entitled "Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2003.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Fab 17b light chain and Fab 17b heavy chain.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Fab 17b light chain Not available
Homo sapienssearch Not available 214 100%
C Fab 17b light chain Not available
Homo sapienssearch Not available 214 100%
B Fab 17b heavy chain Not available
Homo sapienssearch Not available 228 100%
D Fab 17b heavy chain Not available
Homo sapienssearch Not available 228 100%


Chain Structural classification (SCOP) Structural classification (CATH)
A, C V set domains (antibody variable domain-like)search, C1 set domains (antibody constant domain-like)search Immunoglobulinssearch
B, D V set domains (antibody variable domain-like)search, C1 set domains (antibody constant domain-like)search Immunoglobulinssearch
Chain InterPro annotation
A, C Immunoglobulin/major histocompatibility complex, conserved sitesearch Immunoglobulin V-set, subgroupsearch Immunoglobulin C1-setsearch Immunoglobulin-like domainsearch Immunoglobulin V-set domainsearch Immunoglobulin-like foldsearch
B, D Immunoglobulin/major histocompatibility complex, conserved sitesearch Immunoglobulin V-set, subgroupsearch Immunoglobulin C1-setsearch Immunoglobulin-like domainsearch Immunoglobulin V-set domainsearch Immunoglobulin-like foldsearch