1rxr Summary

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HIGH RESOLUTION SOLUTION STRUCTURE OF THE RETINOID X RECEPTOR DNA BINDING DOMAIN, NMR, 20 STRUCTURE

The structure was published by Holmbeck, S.M., Foster, M.P., Casimiro, D.R., Sem, D.S., Dyson, H.J., and Wright, P.E., in 1998 in a paper entitled "High-resolution solution structure of the retinoid X receptor DNA-binding domain." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1998.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of RETINOIC ACID RECEPTOR-ALPHA. This molecule has the UniProt identifier P19793 (RXRA_HUMAN)search. The sample contained 83 residues which is < 90% of the natural sequence. Out of 83 residues 83 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A RETINOIC ACID RECEPTOR-ALPHA P19793 (130-212) (RXRA_HUMAN)search Homo sapienssearch 98% 83 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P19793 (130 - 212) RETINOIC ACID RECEPTOR-ALPHA Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P19793) Nuclear receptorsearch Erythroid Transcription Factor GATA-1, subunit Asearch PF00105: Zinc finger, C4 type (two domains)search

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A (P19793) zinc ion bindingsearch sequence-specific DNA binding transcription factor activitysearch sequence-specific DNA bindingsearch regulation of transcription, DNA-templatedsearch nucleussearch

Chain InterPro annotation
A Zinc finger, nuclear hormone receptor-typesearch Zinc finger, NHR/GATA-typesearch