› 1rxr

Solution NMR

HIGH RESOLUTION SOLUTION STRUCTURE OF THE RETINOID X RECEPTOR DNA BINDING DOMAIN, NMR, 20 STRUCTURE

Released:
DOI: 10.2210/pdb1rxr/pdb
PDB entry 1rxr coloured by chain, ensemble of 20 models, front view.
PDB entry 1rxr coloured by chain, ensemble of 20 models, side view.
PDB entry 1rxr coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
High-resolution solution structure of the retinoid X receptor DNA-binding domain.
Holmbeck SM, Foster MP, Casimiro DR, Sem DS, Dyson HJ, Wright PE
J Mol Biol 281 271-84 (1998)
PMID: 9698548

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148710 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinoic acid receptor RXR-alpha Chain: A
Molecule details ›
Chain: A
Length: 83 amino acids
Theoretical weight: 9.82 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P19793 (Residues: 130-212; Coverage: 18%)
Gene names: NR2B1, RXRA
Sequence domains: Zinc finger, C4 type (two domains)
Structure domains: Erythroid Transcription Factor GATA-1, subunit A

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND RESTRAINED MOLECULAR DYNAMICS
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 review citations

Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm.
Wright et al. (1999)
6 more

7 mentions without citation

The retinoid X receptors and their ligands.
Dawson et al. (2012)
6 more