Structure of human purine nucleoside phosphorylase in complex with Immucillin-H and phosphate
The structure was published by Shi, W., Ting, L.M., Kicska, G.A., et al., Kim, K., Almo, S.C., and Schramm, V.L., in 2004 in a paper entitled "Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2003.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of Purine nucleoside phosphorylase. This molecule has the UniProt identifier P00491 (PNPH_HUMAN). The sample contained 289 residues which is 100% of the natural sequence. Out of 289 residues 282 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms homotrimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: