1rpy Summary

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CRYSTAL STRUCTURE OF THE DIMERIC SH2 DOMAIN OF APS

The structure was published by Hu, J., Liu, J., Ghirlando, R., Saltiel, A.R., and Hubbard, S.R., in 2003 in a paper entitled "Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2003.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of adaptor protein APS.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A adaptor protein APS Q9Z200 (401-510) (SH2B2_RAT)search Rattus norvegicussearch < 90% 114 75%
B adaptor protein APS Q9Z200 (401-510) (SH2B2_RAT)search Rattus norvegicussearch < 90% 114 75%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q9Z200 (401 - 510) adaptor protein APS Rattus norvegicus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B SH2 domainsearch SHC Adaptor Proteinsearch SH2 domainsearch
Chain InterPro annotation
A, B SH2 domainsearch