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CRYSTAL STRUCTURE OF THE DIMERIC SH2 DOMAIN OF APS

Source organism: Rattus norvegicus
Biochemical function: signaling adaptor activity
Biological process: signal transduction
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00017
Domain description: SH2 domain
Occurring in:
  1. SH2B adapter protein 2
The deposited structure of PDB entry 1rpy contains 2 copies of Pfam domain PF00017 (SH2 domain) in SH2B adapter protein 2. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR000980
Domain description: SH2 domain
Occurring in:
  1. SH2B adapter protein 2
IPR036860
Domain description: SH2 domain superfamily
Occurring in:
  1. SH2B adapter protein 2
IPR035058
Domain description: SH2B2, SH2 domain
Occurring in:
  1. SH2B adapter protein 2
IPR030523
Domain description: SH2B adapter protein
Occurring in:
  1. SH2B adapter protein 2

Structure domain

CATH CATH domain
3.30.505.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: SHC Adaptor Protein
Homology: SH2 domain
Occurring in:
  1. SH2B adapter protein 2
The deposited structure of PDB entry 1rpy contains 2 copies of CATH domain 3.30.505.10 (SHC Adaptor Protein) in SH2B adapter protein 2. Showing 1 copy in chain B.
SCOP SCOP annotation
55551
Class: Alpha and beta proteins (a+b)
Fold: SH2-like
Superfamily: SH2 domain
Occurring in:
  1. SH2B adapter protein 2
The deposited structure of PDB entry 1rpy contains 2 copies of SCOP domain 55551 (SH2 domain) in SH2B adapter protein 2. Showing 1 copy in chain B.

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