1rlp Summary

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TWO BINDING ORIENTATIONS FOR PEPTIDES TO SRC SH3 DOMAIN: DEVELOPMENT OF A GENERAL MODEL FOR SH3-LIGAND INTERACTIONS

The structure was published by Feng, S., Chen, J.K., Yu, H., Simon, J.A., and Schreiber, S.L., in 1994 in a paper entitled "Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions." (abstract).

The structure was determined using NMR spectroscopy and deposited in 1994.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely C-SRC TYROSINE KINASE SH3 DOMAIN and PROLINE-RICH LIGAND RLP2 (RALPPLPRY).

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
C C-SRC TYROSINE KINASE SH3 DOMAIN P00523 (77-140) (SRC_CHICK)search Gallus gallussearch < 90% 64 87%
R PROLINE-RICH LIGAND RLP2 (RALPPLPRY) Not available
Not available Not available 9 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P00523 (77 - 140) C-SRC TYROSINE KINASE SH3 DOMAIN Gallus gallus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
C SH3-domainsearch SH3 Domainssearch SH3 domainsearch
R
Chain InterPro annotation
C SH3 domainsearch
R