1rhi

X-ray diffraction
3Å resolution

HUMAN RHINOVIRUS 3 COAT PROTEIN

Released:
Source organism: rhinovirus B3
Primary publication:
Human rhinovirus 3 at 3.0 A resolution.
Structure 4 1205-20 (1996)
PMID: 8939746

Function and Biology Details

Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
hetero 240-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182628 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Capsid protein VP1 Chain: 1
Molecule details ›
Chain: 1
Length: 288 amino acids
Theoretical weight: 32.33 KDa
Source organism: rhinovirus B3
UniProt:
  • Canonical: Q82081 (Residues: 568-855; Coverage: 13%)
Sequence domains: picornavirus capsid protein
Structure domains: Jelly Rolls
Capsid protein VP2 Chain: 2
Molecule details ›
Chain: 2
Length: 262 amino acids
Theoretical weight: 28.7 KDa
Source organism: rhinovirus B3
UniProt:
  • Canonical: Q82081 (Residues: 70-331; Coverage: 12%)
Sequence domains: picornavirus capsid protein
Structure domains: Jelly Rolls
Capsid protein VP3 Chain: 3
Molecule details ›
Chain: 3
Length: 236 amino acids
Theoretical weight: 26.06 KDa
Source organism: rhinovirus B3
UniProt:
  • Canonical: Q82081 (Residues: 332-567; Coverage: 11%)
Sequence domains: picornavirus capsid protein
Structure domains: Jelly Rolls
Capsid protein VP4 Chain: 4
Molecule details ›
Chain: 4
Length: 68 amino acids
Theoretical weight: 7.22 KDa
Source organism: rhinovirus B3
UniProt:
  • Canonical: Q82081 (Residues: 2-69; Coverage: 3%)
Sequence domains: Picornavirus coat protein (VP4)
Structure domains: Picornavirus coat protein VP4

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Unit cell:
a: 397.9Å b: 341.8Å c: 301.7Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.284 0.284 0.288