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PDBe Entry: 1rb0 
CRYSTAL STRUCTURE OF A BINARY COMPLEX OF E. COLI HPPK WITH 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE AT 1.35 ANGSTROM RESOLUTION
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TRANSFERASE
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X-RAY DIFFRACTION
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Resolution: 1.35 Å, R-factor: 13.74%, Free R-factor: 19.98%, Spacegroup: P 21 21 2
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09/11/2004, deposition: 31/10/2003, last revision: 24/02/2009
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Blaszczyk, J.; Ji, X.
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Reaction trajectory of pyrophosphoryl transfer catalyzed by 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase.
STRUCTURE vol:12, pag:467-475 (2004) [PubMed ID 15016362 ]
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PYROPHOSPHOKINASE, PYROPHOSPHORYL TRANSFER, CATALYTIC MECHANISM, FOLATE, HPPK, PTERIN, 6-HYDROXYMETHYL-7, 8-DIHYDROPTERIN, 6-HYDROXYMETHYLPTERIN, TERNARY COMPLEX, BINARY COMPLEX, SUBSTRATE SPECIFICITY, PRODUCT RELEASE, ANTIMICROBIAL AGENT, DRUG DESIGN, X-RAY CRYSTALLOGRAPHY, TRANSFERASE
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2.7.6.3 ExPASy BRENDA (A)
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Escherichia coli 562(A)
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2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) (7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase) (HPPK) (6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase) (PPPK) P26281 (A)
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A
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1hka, 1eqm, 1eq0, 1q0n, 1ex8, 1cbk, 1dy3, 1f9y, 1f9h, 1g4c, 1hq2, 1im6, 1kbr, 1rao
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| A |
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase |
Protein |
P26281 (HPPK_ECOLI)
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158 |
100% |
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| A |
6-HYDROXYMETHYLPTERIN-DIPHOSPHATE |
HH2
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