1ray Summary



The structure was published by Jonsson, B.M., Hakansson, K., and Liljas, A., in 1993 in a paper entitled "The structure of human carbonic anhydrase II in complex with bromide and azide." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.8 Å and deposited in 1993.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of CARBONIC ANHYDRASE II. This molecule has the UniProt identifier P00918 (CAH2_HUMAN)search. The sample contained 259 residues which is 100% of the natural sequence. Out of 259 residues 258 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A CARBONIC ANHYDRASE II P00918 (2-260) (CAH2_HUMAN)search Homo sapienssearch 98% 259 99%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P00918 (2 - 260) CARBONIC ANHYDRASE II Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P00918) Carbonic anhydrasesearch Carbonic Anhydrase IIsearch PF00194: Eukaryotic-type carbonic anhydrasesearch

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A (P00918) one-carbon metabolic processsearch angiotensin-activated signaling pathwaysearch bicarbonate transportsearch positive regulation of osteoclast differentiationsearch positive regulation of cellular pH reductionsearch morphogenesis of an epitheliumsearch response to estrogensearch kidney developmentsearch regulation of intracellular pHsearch small molecule metabolic processsearch response to organic substancesearch positive regulation of dipeptide transmembrane transportsearch regulation of anion transportsearch odontogenesis of dentin-containing toothsearch response to pHsearch positive regulation of synaptic transmission, GABAergicsearch positive regulation of bone resorptionsearch response to zinc ionsearch regulation of chloride transportsearch response to steroid hormonesearch secretionsearch basolateral plasma membranesearch plasma membranesearch cytosolsearch cytoplasmsearch microvillussearch extracellular vesicular exosomesearch membranesearch axonsearch myelin sheathsearch extracellular spacesearch apical part of cellsearch carbonate dehydratase activitysearch lyase activitysearch zinc ion bindingsearch metal ion bindingsearch protein bindingsearch

Chain InterPro annotation
A Alpha carbonic anhydrasesearch Carbonic anhydrase, alpha-class, conserved sitesearch Carbonic anhydrase 2search Carbonic anhydrase, alpha-classsearch