PDBe Entry: 1r6t

crystal structure of human tryptophanyl-tRNA synthetase

Summary

Header

LIGASE

Method

X-RAY DIFFRACTION

Experiment

Resolution: 2.1 Å, R-factor: 20.82%, Free R-factor: 23.86%, Spacegroup: C 1 2 1

Released

06/01/2004, deposition: 16/10/2003, last revision: 24/02/2009

Authors

Yang, X.-L.

; Otero, F.J.

; Skene, R.J.

; McRee, D.E.

; Ribas de Pouplana, L.

; Schimmel, P.

Primary citation

Crystal structures that suggest late development of genetic code components for differentiating aromatic side chains
PROC.NATL.ACAD.SCI.USA

vol:100, pag:15376-15380 (2003) [PubMed ID 14671330 ]

Keywords

Class Ic tRNA synthetase

, Rossmann fold catalytical domain

, anticodon recognition domain

, bound Trp-AMP

, LIGASE

Organism

Homo sapiens(human) 9606

(A B)

Solvent

A, B

Polymers

Id	Name	Type	UniProt	Residues	Observed
A, B	Tryptophanyl-tRNA synthetase	Protein		477	92%

Heterogens