› 1qym

X-ray diffraction
2.8Å resolution

X-ray structure of human gankyrin

Released:
DOI: 10.2210/pdb1qym/pdb
PDB entry 1qym coloured by chain, front view.
PDB entry 1qym coloured by chain, side view.
PDB entry 1qym coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma.
Manjasetty BA, Quedenau C, Sievert V, Büssow K, Niesen F, Delbrück H, Heinemann U
Proteins 55 214-7 (2004)
PMID: 14997555

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131139 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
26S proteasome non-ATPase regulatory subunit 10 Chain: A
Molecule details ›
Chain: A
Length: 227 amino acids
Theoretical weight: 24.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75832 (Residues: 2-226; Coverage: 100%)
Gene name: PSMD10
Sequence domains: Ankyrin repeats (3 copies)
Structure domains: Ankyrin repeat-containing domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P41212
Unit cell:
a: 116.373Å b: 116.373Å c: 74.399Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.187 0.233
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Folding and Stability of Ankyrin Repeats Control Biological Protein Function.
Kumar et al. (2021)
11 other articles

9 mentions without citation

A primer on ankyrin repeat function in TRP channels and beyond.
Gaudet R. (2008)
8 more