1qva Summary



The structure was published by Johnson, E.R. and McKay, D.B., in 1999 in a paper entitled "Crystallographic structure of the amino terminal domain of yeast initiation factor 4A, a representative DEAD-box RNA helicase" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 1999.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of INITIATION FACTOR 4A. This molecule has the UniProt identifier P10081 (IF4A_YEAST)search. The sample contained 223 residues which is < 90% of the natural sequence. Out of 223 residues 209 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A INITIATION FACTOR 4A P10081 (2-224) (IF4A_YEAST)search Saccharomyces cerevisiae S288csearch 100% 223 95%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P10081 (2 - 224) INITIATION FACTOR 4A Saccharomyces cerevisiae

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P10081) Tandem AAA-ATPase domainsearch P-loop containing nucleotide triphosphate hydrolasessearch PF00270: DEAD/DEAH box helicasesearch

Chain ID Molecular function (GO)
A (P10081) nucleic acid bindingsearch ATP bindingsearch ATP-dependent helicase activitysearch

Chain InterPro annotation
A ATP-dependent RNA helicase DEAD-box, conserved sitesearch DEAD/DEAH box helicase domainsearch Helicase superfamily 1/2, ATP-binding domainsearch RNA helicase, DEAD-box type, Q motifsearch P-loop containing nucleoside triphosphate hydrolasesearch